Crizotinib is a targeted cancer medicine used to treat non-small cell lung cancer in patients who have a gene mutation of either ALK-positive or ROS1-positive. It inhibits the production of tyrosine kinase and blocks abnormal proteins like ALK or ROS1, which help in cancer cell growth. This way the tumor is shrunk and cancer advancement is hindered.
Patients may experience nausea, vomiting, diarrhea, constipation, blurred vision, swelling, fatigue, and loss of appetite. In rare cases, there can be some serious effects, such as liver problems, lung inflammation, abnormal heartbeats, and low white blood cell count.